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The antibody against COMMD5 was raised in rabbit using the Human COMMD5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against COMMD5 was raised in rabbit using the Human COMMD5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-53738A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COMMD5 |
| Target Synonyms | COMMD5 antibody; HT002COMM domain-containing protein 5 antibody; Hypertension-related calcium-regulated gene protein antibody; HCaRG antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human COMMD5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZQ3 |
Uniprot Id
Q9GZQ3
Target Species
Human
Target Name
COMMD5
Target Full Name
COMM domain-containing protein 5
Target Function
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. Negatively regulates cell proliferation. Negatively regulates cell cycle G2/M phase transition probably by transactivating p21/CDKN1A through the p53/TP53-independent signaling pathway. Involved in kidney proximal tubule morphogenesis. Down-regulates activation of NF-kappa-B.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Highly expressed in heart, stomach, jejunum, kidney, liver, and adrenal gland. Expression was generally higher in adult organs than in fetal tissues, particularly in heart, kidney, and liver.
Target Research Area
Transcription
Target Synonyms
COMMD5; HT002COMM domain-containing protein 5; Hypertension-related calcium-regulated gene protein; HCaRG
Target Background
Predicted to be involved in proximal tubule morphogenesis. Located in cytosol and nucleoplasm.
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