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The antibody against CPM was raised in rabbit using the Synthesized peptide derived from internal of Human CPM. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CPM was raised in rabbit using the Synthesized peptide derived from internal of Human CPM. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from A549 cells, using CPM antibody.
| Cat.No | ADC-41361A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CPM |
| Target Synonyms | Carboxypeptidase M antibody; CBPM_HUMAN antibody; CPM antibody; Renal carboxypeptidase antibody; Urinary carboxypeptidase B antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CPM. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P14384 |
Uniprot Id
P14384
Target Species
Human
Target Name
CPM
Target Full Name
Carboxypeptidase M
Target Function
Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Peptidase M14 family
Target Synonyms
Carboxypeptidase M; CBPM_HUMAN; CPM; Renal carboxypeptidase; Urinary carboxypeptidase B
Target Background
The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
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