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Rabbit anti-Human CRLS1 Polyclonal Antibody

The antibody against CRLS1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11011A

The antibody against CRLS1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11011A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCRLS1
Target SynonymsCLS; CLS1; GCD10; COSPD57; C20orf155; dJ967N21.6; CRLS1FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHL-60ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1).Target SpeciesHuman
Immunogen SequenceMLALRVARGSWGALRGAAWAPGTRPSKRRACWALLPPVPCCLGCLAERWRLRPAALGLRLPGIGQRNHCSGAGKAAPRPAAGAGAAAEAPGGQWGPASTPSLYENPWTIPUniprot IDQ9UJA2
Background Information
  • Uniprot Id

    Q9UJA2

  • Target Species

    Human

  • Target Name

    CRLS1

  • Target Full Name

    Cardiolipin synthase (CMP-forming)

  • Target Function

    Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.

  • Target Subcellular Location

    Mitochondrion inner membrane; Multi-pass membrane protein.

  • Target Protein Families

    CDP-alcohol phosphatidyltransferase class-I family

  • Target Tissue Specificity

    Highly expressed in tissues such as heart, skeletal muscle and liver.

  • Target Synonyms

    CRLS1; C20orf155; CLS1; Cardiolipin synthase; CMP-forming; CLS; Protein GCD10 homolog

  • Target Background

    This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function.

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