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The antibody against CYP4F22 was raised in rabbit using the Recombinant Human Cytochrome P450 4F22 protein (413-507AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against CYP4F22 was raised in rabbit using the Recombinant Human Cytochrome P450 4F22 protein (413-507AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-08231A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CYP4F22 |
| Target Synonyms | CYP4F22Cytochrome P450 4F22 antibody; EC 1.14.14.- antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cytochrome P450 4F22 protein (413-507AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6NT55 |
Uniprot Id
Q6NT55
Target Species
Human
Target Name
CYP4F22
Target Full Name
Ultra-long-chain fatty acid omega-hydroxylase
Target Function
A cytochrome P450 monooxygenase involved in epidermal ceramide biosynthesis. Hydroxylates the terminal carbon (omega-hydroxylation) of ultra-long-chain fatty acyls (C28-C36) prior to ceramide synthesis. Contributes to the synthesis of three classes of omega-hydroxy-ultra-long chain fatty acylceramides having sphingosine, 6-hydroxysphingosine and phytosphingosine bases, all major lipid components that underlie the permeability barrier of the stratum corneum. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
Target Involvement
Ichthyosis, congenital, autosomal recessive 5 (ARCI5)
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type I membrane protein. Microsome membrane; Single-pass type I membrane protein.
Target Protein Families
Cytochrome P450 family
Target Synonyms
CYP4F22Cytochrome P450 4F22; EC 1.14.14.-
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