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Rabbit anti-Human DBF4 Polyclonal Antibody

The antibody against DBF4 was raised in rabbit using the Recombinant Human Protein DBF4 homolog A protein (101-281AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-08114A

The antibody against DBF4 was raised in rabbit using the Recombinant Human Protein DBF4 homolog A protein (101-281AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-08114A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDBF4
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein DBF4 homolog A protein (101-281AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBU7
Background Information
  • Uniprot Id

    Q9UBU7

  • Target Species

    Human

  • Target Name

    DBF4

  • Target Full Name

    Protein DBF4 homolog A

  • Target Function

    Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Highly expressed in testis and thymus. Expressed also in most cancer cells lines.

  • Target Synonyms

    Activator of S phase kinase; ASK; CHIF; Chiffon homolog A; DBF4; DBF4 homolog (S. cerevisiae); DBF4 homolog; DBF4 type zinc finger containing protein 1; DBF4 zinc finger A; DBF4 zinc finger; DBF4; S. cerevisiae; homolog of; DBF4-type zinc finger-containing protein 1; DBF4A; DBF4A_HUMAN; Dumbbell former 4; S. cerevisiae; homolog of; OTTHUMP00000161661; Protein DBF4 homolog A; ZDBF1; Zinc finger; DBF-type containing 1

  • Target Background

    Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in positive regulation of nuclear cell cycle DNA replication and regulation of cell cycle phase transition. Located in nuclear body.

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