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The antibody against DBR1 was raised in rabbit using the Recombinant Human Lariat debranching enzyme protein (1-220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against DBR1 was raised in rabbit using the Recombinant Human Lariat debranching enzyme protein (1-220AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human thyroid tissue using DBR1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human gastric cancer using DBR1 Antibody at dilution of 1:1002
| Cat.No | ADC-14898A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DBR1 |
| Target Synonyms | DBR1 antibody; DBR1_HUMAN antibody; Debranching enzyme homolog 1 (S. cerevisiae) antibody; Lariat debranching enzyme antibody; RNA lariat debranching enzyme antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Lariat debranching enzyme protein (1-220AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UK59 |
Uniprot Id
Q9UK59
Target Species
Human
Target Name
DBR1
Target Full Name
Lariat debranching enzyme
Target Function
Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.
Target Subcellular Location
Nucleus.
Target Protein Families
Lariat debranching enzyme family
Target Synonyms
DBR1; DBR1_HUMAN; Debranching enzyme homolog 1 (S. cerevisiae) ; Lariat debranching enzyme; RNA lariat debranching enzyme
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