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The antibody against DCT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human DCT (NP_001913.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DCT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human DCT (NP_001913.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-11352A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DCT |
| Target Synonyms | OCA8; TRP-2; TYRP2; DCT | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, A-375, MCF7, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human DCT (NP_001913.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P40126 | Immunogen Sequence |
Uniprot Id
P40126
Target Species
Human
Target Name
DCT
Target Full Name
L-dopachrome tautomerase
Target Function
Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
Target Subcellular Location
Melanosome membrane; Single-pass type I membrane protein. Melanosome.
Target Protein Families
Tyrosinase family
Target Research Area
others
Target Synonyms
L dopachrome tautomerase; DCT; Dopachrome delta isomerase; Dopachrome tautomerase; Dopachrome tautomerase dopachrome delta isomerase; tyrosine related protein 2; DT; EC 5.3.3.12; L dopachrome Delta isomerase; L-dopachrome Delta-isomerase; L-dopachrome tautomerase; TRP 2; TRP-2; TRP2; Tyrosinase related protein 2; Tyrosinase-related protein 2; TYRP2; TYRP2_HUMAN
Target Background
Predicted to enable dopachrome isomerase activity. Involved in response to blue light. Located in intracellular membrane-bounded organelle and plasma membrane. Implicated in oculocutaneous albinism.
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