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Rabbit anti-Human DECR1 Polyclonal Antibody

The antibody against DECR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11152A

The antibody against DECR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11152A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDECR1
Target SynonymsDECR; NADPH; SDR18C1; DECR1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse heart, Mouse liver, SK-BR-3ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 35-335 of human DECR1 (NP_001350.1).Target SpeciesHuman
Uniprot IDQ16698Immunogen Sequence
Background Information
  • Uniprot Id

    Q16698

  • Target Species

    Human

  • Target Name

    DECR1

  • Target Full Name

    2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

  • Target Function

    Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

  • Target Involvement

    2,4-dienoyl-CoA reductase deficiency (DECRD)

  • Target Subcellular Location

    Mitochondrion.

  • Target Protein Families

    Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily

  • Target Tissue Specificity

    Heart = liver = pancreas > kidney >> skeletal muscle = lung.

  • Target Synonyms

    1200012F07Rik; 2; 2,4 dienoyl CoA reductase [NADPH]; 2,4 dienoyl CoA reductase 1; 2,4 dienoyl CoA reductase mitochondrial; 2,4-dienoyl-CoA reductase; mitochondrial; 4 enoyl CoA reductase; 4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; DECR 1; DECR; DECR_HUMAN; DECR1; Nadph; OTTMUSP00000004962; RP23-338J24.3; SDR18C1; Short chain dehydrogenase/reductase family 18C member 1

  • Target Background

    Enables 2, 4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Involved in fatty acid beta-oxidation. Located in cytosol; mitochondrion; and nucleoplasm. Part of catalytic complex.

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