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The antibody against DECR1 was raised in rabbit using the Synthetic peptide of Human DECR1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against DECR1 was raised in rabbit using the Synthetic peptide of Human DECR1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-26825A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DECR1 |
| Target Synonyms | 1200012F07Rik antibody; 2 antibody; 2, 4 dienoyl CoA reductase [NADPH] antibody; 2, 4 dienoyl CoA reductase 1 antibody; 2, 4 dienoyl CoA reductase mitochondrial antibody; 2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human DECR1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16698 |
Uniprot Id
Q16698
Target Species
Human
Target Name
DECR1
Target Full Name
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial
Target Function
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in mitochondria. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.
Target Involvement
2,4-dienoyl-CoA reductase deficiency (DECRD)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily
Target Tissue Specificity
Heart = liver = pancreas > kidney >> skeletal muscle = lung.
Target Synonyms
1200012F07Rik; 2; 2,4 dienoyl CoA reductase [NADPH]; 2,4 dienoyl CoA reductase 1; 2,4 dienoyl CoA reductase mitochondrial; 2,4-dienoyl-CoA reductase; mitochondrial; 4 enoyl CoA reductase; 4-dienoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase [NADPH]; DECR 1; DECR; DECR_HUMAN; DECR1; Nadph; OTTMUSP00000004962; RP23-338J24.3; SDR18C1; Short chain dehydrogenase/reductase family 18C member 1
Target Background
Enables 2, 4-dienoyl-CoA reductase (NADPH) activity; NADPH binding activity; and identical protein binding activity. Involved in fatty acid beta-oxidation. Located in cytosol; mitochondrion; and nucleoplasm. Part of catalytic complex.
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