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The antibody against DENND2D was raised in rabbit using the Recombinant Human DENN domain-containing protein 2D protein (1-233AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against DENND2D was raised in rabbit using the Recombinant Human DENN domain-containing protein 2D protein (1-233AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-25075A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DENND2D |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human DENN domain-containing protein 2D protein (1-233AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H6A0 |
Uniprot Id
Q9H6A0
Target Species
Human
Target Name
DENND2D
Target Full Name
DENN domain-containing protein 2D
Target Function
Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
In bronchial mucosa, mainly expressed in ciliated and basal epithelial cells and weakly in alveolar cells (at protein level). Tends to be down-regulated in lung cancers, immortalized bronchial epithelial cell lines and precancerous lesions.
Target Synonyms
2010308M01Rik; AI451421; DEN2D_HUMAN; DENN domain containing 2D; DENN domain-containing protein 2D; DENN/MADD domain containing 2D; DENND2D; FLJ22457; MGC6915; RGD1305120; RP5-1180E21.2
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