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The antibody against DHCR7 was raised in rabbit using the Recombinant Human 7-dehydrocholesterol reductase protein (63-147AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against DHCR7 was raised in rabbit using the Recombinant Human 7-dehydrocholesterol reductase protein (63-147AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-04371A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DHCR7 |
| Target Synonyms | DHCR7; D7SR; 7-dehydrocholesterol reductase; 7-DHC reductase; Delta7-sterol reductase; Sterol Delta(7-reductase; Sterol reductase SR-2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 7-dehydrocholesterol reductase protein (63-147AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBM7 |
Uniprot Id
Q9UBM7
Target Species
Human
Target Name
DHCR7
Target Full Name
7-dehydrocholesterol reductase
Target Function
7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7-dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien-3beta-ol, two intermediates in that pathway.
Target Involvement
Smith-Lemli-Opitz syndrome (SLOS)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
ERG4/ERG24 family
Target Tissue Specificity
Widely expressed. Most abundant in adrenal gland, liver, testis, and brain.
Target Synonyms
DHCR7; D7SR; 7-dehydrocholesterol reductase; 7-DHC reductase; Delta7-sterol reductase; Sterol Delta(7-reductase; Sterol reductase SR-2
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