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Rabbit anti-Human DNM1 Polyclonal Antibody

The antibody against DNM1 was raised in rabbit using the Peptide sequence around aa.774~778(S-P-T-S-S) derived from Human Dynamin 1 as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.

ADC-43103A

The antibody against DNM1 was raised in rabbit using the Peptide sequence around aa.774~778(S-P-T-S-S) derived from Human Dynamin 1 as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-43103A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDNM1
Target SynonymsB dynamin antibody; D100 antibody; DNM 1 antibody; DNM antibody; DNM1 antibody; DYN1_HUMAN antibody; Dynamin antibody; Dynamin-1 antibody; Dynamin1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+)
Purification MethodAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.ApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionPeptide sequence around aa.774~778(S-P-T-S-S) derived from Human Dynamin 1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ05193
Background Information
  • Uniprot Id

    Q05193

  • Target Species

    Human

  • Target Name

    DNM1

  • Target Full Name

    Dynamin-1

  • Target Function

    Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.

  • Target Involvement

    Epileptic encephalopathy, early infantile, 31 (EIEE31)

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Note=Microtubule-associated.

  • Target Protein Families

    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family

  • Target Research Area

    Neuroscience

  • Target Synonyms

    B dynamin; D100; DNM 1; DNM; DNM1; DYN1_HUMAN; Dynamin; Dynamin-1; Dynamin1

  • Target Background

    This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

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