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The antibody against DUOX2 was raised in rabbit using the Recombinant Human Dual oxidase 2 protein (1-100AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DUOX2 was raised in rabbit using the Recombinant Human Dual oxidase 2 protein (1-100AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human small intestine tissue using DUOX2 Antibody at dilution of 1:50
Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, PC3 whole cell lysate, 293 whole cell lysate, Ntera-2 whole cell lysate All lanes: DUOX2 antibody at 1:500 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 176 kDa Observed band size: 176 kDa2
| Cat.No | ADC-16365A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DUOX2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dual oxidase 2 protein (1-100AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NRD8 |
Uniprot Id
Q9NRD8
Target Species
Human
Target Name
DUOX2
Target Full Name
Dual oxidase 2
Target Function
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Target Involvement
Thyroid dyshormonogenesis 6 (TDH6)
Target Subcellular Location
Apical cell membrane; Multi-pass membrane protein. Cell junction.
Target Protein Families
Peroxidase family
Target Tissue Specificity
Expressed in colon, small intestine, duodenum and tracheal surface epithelial cells (at protein level). Expressed in thyrocytes. Also detected in kidney, liver, lung, pancreas, prostate, salivary glands, rectum and testis.
Target Synonyms
Dual oxidase 2; Dual oxidase like domains 2; Dual oxidase2; DUOX2; DUOX2_HUMAN; Flavoprotein NADPH oxidase; Large NOX 2; LNOX2; Long NOX 2; NADH/NADPH thyroid oxidase p138 tox; NADH/NADPH thyroid oxidase p138-tox; NADPH oxidase/peroxidase DUOX2; NADPH thyroid oxidase 2; Nicotinamide adenine dinucleotide phosphate oxidase; NOXEF2; p138 thyroid oxidase; P138 TOX; TDH6; THOX2; Thyroid oxidase 2
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