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Rabbit anti-Human DZIP3 Polyclonal Antibody

The antibody against DZIP3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human DZIP3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-33253A

The antibody against DZIP3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human DZIP3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-33253A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDZIP3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human DZIP3.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ86Y13
Background Information
  • Uniprot Id

    Q86Y13

  • Target Species

    Human

  • Target Name

    DZIP3

  • Target Full Name

    E3 ubiquitin-protein ligase DZIP3

  • Target Function

    E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.

  • Target Synonyms

    DZIP3; KIAA0675E3 ubiquitin-protein ligase DZIP3; EC 2.3.2.27; DAZ-interacting protein 3; RING-type E3 ubiquitin transferase DZIP3; RNA-binding ubiquitin ligase of 138 kDa; hRUL138

  • Target Background

    Enables several functions, including phosphatase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-protein transferase activity. Involved in protein polyubiquitination. Located in cytoplasm.

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