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The antibody against ECI1 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human DCI. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against ECI1 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human DCI. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of HepG2 cells using DCI Polyclonal Antibody
| Cat.No | ADC-37121A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ECI1 |
| Target Synonyms | 2 trans enoyl Coenzyme A isomerase antibody; 3, 2 trans enoyl Coenzyme A isomerase) antibody; Dodecenoyl Coenzyme A delta isomerase 3, 2 trans-enoyl-CoA isomerase antibody; 3, 2-trans-enoyl-CoA isomerase antibody; 3 antibody; 3, 2-trans-enoyl-CoA isomerase; mitochondrial antibody; Acetylene allene isomerase antibody; D2-enoyl-CoA isomerase antibody; D3 antibody; D3, D2 enoyl CoA isomerase antibody; DCI antibody; DCI protein antibody; delta(2)-enoyl-CoA isomerase antibody; Delta(3) antibody; Delta(3) | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human DCI. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P42126 |
Uniprot Id
P42126
Target Species
Human
Target Name
ECI1
Target Full Name
Enoyl-CoA delta isomerase 1, mitochondrial
Target Function
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Enoyl-CoA hydratase/isomerase family
Target Tissue Specificity
Expressed in liver (at protein level).
Target Synonyms
2-trans-enoyl-CoA isomerase; 3; 3,2 trans enoyl Coenzyme A isomerase ; 3,2 trans-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase; mitochondrial; Acetylene allene isomerase; D2-enoyl-CoA isomerase; D3; D3,D2 enoyl CoA isomerase ; DCI; DCI protein ; delta(2)-enoyl-CoA isomerase; Delta(3); Delta(3),Delta(2) enoyl CoA isomerase ; Delta3; delta2 enoyl CoA isomerase; Dodecenoyl CoA delta Isomerase; Dodecenoyl CoA isomerase; Dodecenoyl Coenzyme A delta isomerase ; Dodecenoyl Coenzyme A delta isomerase (3,2 trans enoyl Coenzyme A isomerase); Dodecenoyl Coenzyme A delta isomerase 3,2 trans enoyl Coenzyme A isomerase; isoform CRA a; Dodecenoyl-CoA isomerase; ECI1; ECI1_HUMAN; Enoyl-CoA delta isomerase 1; enoyl-CoA delta isomerase 1; mitochondrial; mitochondrial
Target Background
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
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