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The antibody against EDEM1 was raised in rabbit using the Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against EDEM1 was raised in rabbit using the Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-02014A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EDEM1 |
| Target Synonyms | EDEM1 antibody; EDEM antibody; KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92611 |
Uniprot Id
Q92611
Target Species
Human
Target Name
EDEM1
Target Full Name
ER degradation-enhancing alpha-mannosidase-like protein 1
Target Function
Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyl hydrolase 47 family
Target Synonyms
EDEM1; EDEM; KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1
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