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The antibody against ENPP4 was raised in rabbit using the Synthetic peptide of Human ENPP4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ENPP4 was raised in rabbit using the Synthetic peptide of Human ENPP4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-26777A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ENPP4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human ENPP4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y6X5 |
Uniprot Id
Q9Y6X5
Target Species
Human
Target Name
ENPP4
Target Full Name
Bis(5'-adenosyl)-triphosphatase ENPP4
Target Function
Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Nucleotide pyrophosphatase/phosphodiesterase family
Target Tissue Specificity
Expressed on the surface of vascular endothelia.
Target Synonyms
NPP4; ENPP4
Target Background
Enables bis(5'-adenosyl)-triphosphatase activity. Involved in positive regulation of blood coagulation and purine ribonucleoside catabolic process. Located in extracellular exosome and membrane.
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