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The antibody against ESAM was raised in rabbit using the Recombinant Human Endothelial cell-selective adhesion molecule protein (30-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ESAM was raised in rabbit using the Recombinant Human Endothelial cell-selective adhesion molecule protein (30-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using ESAM Antibody at dilution of 1:100
| Cat.No | ADC-49690A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ESAM |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Endothelial cell-selective adhesion molecule protein (30-248AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96AP7 |
Uniprot Id
Q96AP7
Target Species
Human
Target Name
ESAM
Target Full Name
Endothelial cell-selective adhesion molecule
Target Function
Can mediate aggregation most likely through a homophilic molecular interaction.
Target Subcellular Location
Cell junction, adherens junction. Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein.
Target Tissue Specificity
Highly expressed in endothelial cells.
Target Research Area
Cell Adhesion
Target Synonyms
2310008D05Rik; Endothelial cell adhesion molecule; Endothelial cell selective adhesion molecule; Endothelial cell-selective adhesion molecule; Esam; ESAM_HUMAN; HUEL (C4orf1) interacting protein ; LP4791 protein ; W117m
Target Background
Enables cell-cell adhesion mediator activity. Involved in several processes, including bicellular tight junction assembly; cell-cell adhesion; and regulation of actin cytoskeleton organization. Located in cell-cell junction and plasma membrane. Part of protein-containing complex.
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