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The antibody against ESD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human ESD (NP_001975.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against ESD was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human ESD (NP_001975.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-03132A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ESD |
| Target Synonyms | FGH; ESD | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, 293T, HepG2, Jurkat, MCF7 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-282 of human ESD (NP_001975.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P10768 | Immunogen Sequence |
Uniprot Id
P10768
Target Species
Human
Target Name
ESD
Target Full Name
S-formylglutathione hydrolase
Target Function
Serine hydrolase involved in the detoxification of formaldehyde.
Target Subcellular Location
Cytoplasm. Cytoplasmic vesicle.
Target Protein Families
Esterase D family
Target Synonyms
EC 3.1.2.12 ; Es-10; Es10; ESD; ESTD_HUMAN; Esterase 10; Esterase D; Esterase D formylglutathione hydrolase; FGH; FGH, included; FLJ11763; Methylumbelliferyl acetate deacetylase; MGC139609; OTTHUMP00000018374 ; OTTHUMP00000040929 ; S formylglutathione hydrolase; S-formylglutathione hydrolase; S-formylglutathione hydrolase, included; Sid 478; sid478
Target Background
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease.
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