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The antibody against FAM35A was raised in rabbit using the Synthesized peptide derived from internal of Human FAM35A/B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against FAM35A was raised in rabbit using the Synthesized peptide derived from internal of Human FAM35A/B. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from Jurkat cells, using FAM35A/B antibody.
| Cat.No | ADC-41015A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FAM35A |
| Target Synonyms | SHLD2 antibody; FAM35A antibody; RINN2 antibody; Shieldin complex subunit 2 antibody; Protein FAM35A antibody; RINN1-REV7-interacting novel NHEJ regulator 2 antibody; Shield complex subunit 2 antibody | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human FAM35A/B. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86V20 |
Uniprot Id
Q86V20
Target Species
Human
Target Name
FAM35A
Target Full Name
Shieldin complex subunit 2
Target Function
Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
FAM35 family
Target Synonyms
SHLD2; FAM35A; RINN2; Shieldin complex subunit 2; Protein FAM35A; RINN1-REV7-interacting novel NHEJ regulator 2; Shield complex subunit 2
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