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The antibody against FAM49B was raised in rabbit using the Recombinant Human Protein FAM49B protein (1-324AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against FAM49B was raised in rabbit using the Recombinant Human Protein FAM49B protein (1-324AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-44843A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FAM49B |
| Target Synonyms | BM 009 antibody; FA49B_HUMAN antibody; Fam49b antibody; Family with sequence similarity 49; member B antibody; L1 antibody; Protein FAM49B antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein FAM49B protein (1-324AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NUQ9 |
Uniprot Id
Q9NUQ9
Target Species
Human
Target Name
CYRIB
Target Full Name
CYFIP-related Rac1 interactor B
Target Function
Negatively regulates RAC1 signaling and RAC1-driven cytoskeletal remodeling. Regulates chemotaxis, cell migration and epithelial polarization by controlling the polarity, plasticity, duration and extent of protrusions. Limits Rac1 mediated activation of the Scar/WAVE complex, focuses protrusion signals and regulates pseudopod complexity by inhibiting Scar/WAVE-induced actin polymerization. Protects against Salmonella bacterial infection. Attenuates processes such as macropinocytosis, phagocytosis and cell migration and restrict sopE-mediated bacterial entry. Restricts also infection mediated by Mycobacterium tuberculosis and Listeria monocytogenes. Involved in the regulation of mitochondrial dynamics and oxidative stress.
Target Subcellular Location
Membrane; Lipid-anchor. Mitochondrion.
Target Protein Families
FAM49 family
Target Research Area
Cell Biology
Target Synonyms
BM 009; FA49B_HUMAN; Fam49b; Family with sequence similarity 49; member B; L1; Protein FAM49B
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