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The antibody against FATE1 was raised in rabbit using the Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against FATE1 was raised in rabbit using the Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-18921A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FATE1 |
| Target Synonyms | FATE1; FATE; Fetal and adult testis-expressed transcript protein; Cancer/testis antigen 43; CT43; Tumor antigen BJ-HCC-2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q969F0 |
Uniprot Id
Q969F0
Target Species
Human
Target Name
FATE1
Target Full Name
Fetal and adult testis-expressed transcript protein
Target Function
Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.
Target Subcellular Location
Mitochondrion. Mitochondrion outer membrane. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.
Target Tissue Specificity
Testis-specific in fetus (aged from 6 to 11 weeks). In adult, expressed predominantly in testis, with some expression in lung, heart, kidney, adrenal gland and whole brain. Highly expressed in certain types of cancer tissues such as hepatocellular carcino
Target Synonyms
FATE1; FATE; Fetal and adult testis-expressed transcript protein; Cancer/testis antigen 43; CT43; Tumor antigen BJ-HCC-2
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