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Rabbit anti-Human FATE1 Polyclonal Antibody

The antibody against FATE1 was raised in rabbit using the Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-18921A

The antibody against FATE1 was raised in rabbit using the Recombinant Human Fetal and adult testis-expressed transcript protein (1-162AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-18921A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFATE1
Target SynonymsFATE1; FATE; Fetal and adult testis-expressed transcript protein; Cancer/testis antigen 43; CT43; Tumor antigen BJ-HCC-2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Fetal and adult testis-expressed transcript protein (1-162AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ969F0
Background Information
  • Uniprot Id

    Q969F0

  • Target Species

    Human

  • Target Name

    FATE1

  • Target Full Name

    Fetal and adult testis-expressed transcript protein

  • Target Function

    Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling.

  • Target Subcellular Location

    Mitochondrion. Mitochondrion outer membrane. Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side.

  • Target Tissue Specificity

    Testis-specific in fetus (aged from 6 to 11 weeks). In adult, expressed predominantly in testis, with some expression in lung, heart, kidney, adrenal gland and whole brain. Highly expressed in certain types of cancer tissues such as hepatocellular carcino

  • Target Synonyms

    FATE1; FATE; Fetal and adult testis-expressed transcript protein; Cancer/testis antigen 43; CT43; Tumor antigen BJ-HCC-2

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