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Rabbit anti-Human FCER1A Polyclonal Antibody

The antibody against FCER1A was raised in rabbit using the Recombinant Human High affinity immunoglobulin epsilon receptor subunit alpha protein as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-16030A

The antibody against FCER1A was raised in rabbit using the Recombinant Human High affinity immunoglobulin epsilon receptor subunit alpha protein as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-16030A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFCER1A
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer50% Glycerol, BS with 0.1% Sodium Azide, pH 7.3
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human High affinity immunoglobulin epsilon receptor subunit alpha proteinTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP12319
Background Information
  • Uniprot Id

    P12319

  • Target Species

    Human

  • Target Name

    FCER1A

  • Target Full Name

    High affinity immunoglobulin epsilon receptor subunit alpha

  • Target Function

    Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Research Area

    Immunology

  • Target Synonyms

    Fc epsilon RI alpha; Fc epsilon RI alpha chain ; Fc epsilon RI alpha-chain; Fc fragment of IgE high affinity I receptor for alpha polypeptide; Fc fragment of IgE; high affinity I; receptor for; alpha subunit; Fc fragment of IgE; high affinity I; receptor for; alpha polypeptide; Fc IgE receptor alpha polypeptide; Fc IgE receptor; alpha chain; Fc IgE receptor; alpha polypeptide; Fc of IgE high affinity I receptor for alpha polypeptide; Fc-epsilon RI-alpha; FCE 1A; FCE1A; FCER 1A; Fcer1a; FCERA_HUMAN; FceRI alpha; FcERI; high affinity IgE receptor; High affinity immunoglobulin epsilon receptor alpha subunit; high affinity immunoglobulin epsilon receptor alpha-subunit; High affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor alpha subunit; IgE Fc receptor subunit alpha; Immunoglobulin E receptor high affinity of mast cells alpha polypeptide ; immunoglobulin E receptor; high-affinity; of mast cells; alpha polypeptide

  • Target Background

    The immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine that are responsible for allergy symptoms are released. This receptor is comprised of an alpha subunit, a beta subunit, and two gamma subunits. The protein encoded by this gene represents the alpha subunit.

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