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The antibody against FGF21 was raised in rabbit using the Recombinant Human Fibroblast growth factor 21 protein (29-209AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against FGF21 was raised in rabbit using the Recombinant Human Fibroblast growth factor 21 protein (29-209AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-50937A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Fgf21 |
| Target Synonyms | FGF 21 antibody; FGF-21 antibody; Fgf21 antibody; FGF21_HUMAN antibody; FGFL antibody; Fibroblast growth factor 21 antibody; PRO10196 antibody; UNQ3115 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Fibroblast growth factor 21 protein (29-209AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NSA1 |
Uniprot Id
Q9NSA1
Target Species
Human
Target Name
FGF21
Target Full Name
Fibroblast growth factor 21
Target Function
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity.
Target Subcellular Location
Secreted.
Target Protein Families
Heparin-binding growth factors family
Target Research Area
Signal Transduction
Target Synonyms
FGF 21; FGF-21; Fgf21; FGF21_HUMAN; FGFL; Fibroblast growth factor 21; PRO10196; UNQ3115
Target Background
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue.
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