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Rabbit anti-Human FLI1 Polyclonal Antibody

The antibody against FLI1 was raised in rabbit using the Human FLI1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-48540A

The antibody against FLI1 was raised in rabbit using the Human FLI1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-48540A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFLI1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman FLI1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ01543
Background Information
  • Uniprot Id

    Q01543

  • Target Species

    Human

  • Target Name

    FLI1

  • Target Full Name

    Friend leukemia integration 1 transcription factor

  • Target Function

    Sequence-specific transcriptional activator. Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.

  • Target Involvement

    Ewing sarcoma (ES); Bleeding disorder, platelet-type 21 (BDPLT21)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Research Area

    Cancer

  • Target Synonyms

    (Proto-oncogene Fli-1)(Transcription factor ERGB)

  • Target Background

    This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

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