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Rabbit anti-Human FOXE3 Polyclonal Antibody

The antibody against FOXE3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human FoxE3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-35851A

The antibody against FOXE3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human FoxE3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-35851A ClonalityPolyclonal
Host SpeciesRabbitTarget NameFOXE3
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human FoxE3.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ13461
Background Information
  • Uniprot Id

    Q13461

  • Target Species

    Human

  • Target Name

    FOXE3

  • Target Full Name

    Forkhead box protein E3

  • Target Function

    Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation. Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm. Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye.

  • Target Involvement

    Anterior segment dysgenesis 2 (ASGD2); Cataract 34, multiple types (CTRCT34); Aortic aneurysm, familial thoracic 11 (AAT11)

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    Drosphilia Forkhead Homolog Like 12; FKHL 12; FKHL12; Forkhead Box E3; Forkhead box protein E3; Forkhead Related Activator 8; Forkhead related protein FKHL12; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; Foxe3; FOXE3 forkhead box E3 ; FOXE3_HUMAN; FREAC 8; FREAC-8; FREAC8

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