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The antibody against FST was raised in rabbit using the Synthetic peptide of Human FST as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against FST was raised in rabbit using the Synthetic peptide of Human FST as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using FST Antibody(FST Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using FST Antibody(FST Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200)2
| Cat.No | ADC-28469A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FST |
| Target Synonyms | Activin binding protein antibody; Activin-binding protein antibody; Follistatin antibody; FS antibody; fst antibody; FST_HUMAN antibody; Human follistatin gene antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human FST | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P19883 |
Uniprot Id
P19883
Target Species
Human
Target Name
FST
Target Full Name
Follistatin
Target Function
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Target Subcellular Location
Secreted.
Target Tissue Specificity
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid. In the embryo, strong expression is seen in the palatal epithelia, including the medial edge epithelial and midline epithelial seam of the palatal shelves. Less pronoun
Target Synonyms
Activin binding protein ; Activin-binding protein; Follistatin; FS; fst; FST_HUMAN; Human follistatin gene
Target Background
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
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