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The antibody against G2E3 was raised in rabbit using the Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase protein (240-337AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against G2E3 was raised in rabbit using the Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase protein (240-337AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-05683A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | G2E3 |
| Target Synonyms | G2E3 antibody; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase antibody; EC 2.3.2.26 antibody; G2/M phase-specific HECT-type E3 ubiquitin transferase antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase protein (240-337AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7L622 |
Uniprot Id
Q7L622
Target Species
Human
Target Name
G2E3
Target Full Name
G2/M phase-specific E3 ubiquitin-protein ligase
Target Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.
Target Subcellular Location
Nucleus, nucleolus. Cytoplasm.
Target Tissue Specificity
Predominantly expressed in brain, liver, kidney, testes and ovary.
Target Synonyms
G2E3; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase; EC 2.3.2.26; G2/M phase-specific HECT-type E3 ubiquitin transferase
Target Background
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in apoptotic process and protein ubiquitination. Predicted to act upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Located in Golgi apparatus and cytosol.
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