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The antibody against GABPA was raised in rabbit using the Recombinant Human GA-binding protein alpha chain protein (268-372AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against GABPA was raised in rabbit using the Recombinant Human GA-binding protein alpha chain protein (268-372AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-02784A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GABPA |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human GA-binding protein alpha chain protein (268-372AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q06546 |
Uniprot Id
Q06546
Target Species
Human
Target Name
GABPA
Target Full Name
GA-binding protein alpha chain
Target Function
Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Synonyms
NFT2; NRF2; NRF2A; E4TF1A; E4TF1-60; RCH04A07; GABPA
Target Background
This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene.
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