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The antibody against GNB1 was raised in rabbit using the Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 protein (157-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against GNB1 was raised in rabbit using the Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 protein (157-248AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-11121A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GNB1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 protein (157-248AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P62873 |
Uniprot Id
P62873
Target Species
Human
Target Name
GNB1
Target Full Name
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Target Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Target Involvement
Mental retardation, autosomal dominant 42 (MRD42)
Target Protein Families
WD repeat G protein beta family
Target Synonyms
Beta subunit signal transducing proteins GS/GI ; G protein beta 1 subunit ; GBB1; GBB1_HUMAN; gnb1; Guanine nucleotide binding protein (G protein) beta polypeptide 1; Guanine nucleotide binding protein beta 1 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Transducin beta chain 1
Target Background
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants.
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