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The antibody against GNL3L was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GNL3L. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against GNL3L was raised in rabbit using the Synthesized peptide derived from the Internal region of Human GNL3L. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of HT29 cells using GNL3L Polyclonal Antibody
Western Blot analysis of NIH-3T3 LOVO cells using GNL3L Polyclonal Antibody2
Western blot analysis of mouse-brain HELA KB SH-SY5Y 293T 3T3 Mouse-kidney lysis using GNL3L antibody.3
| Cat.No | ADC-38578A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GNL3L |
| Target Synonyms | GNL3LGuanine nucleotide-binding protein-like 3-like protein antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human GNL3L. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NVN8 |
Uniprot Id
Q9NVN8
Target Species
Human
Target Name
GNL3L
Target Full Name
Guanine nucleotide-binding protein-like 3-like protein
Target Function
Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP.
Target Subcellular Location
Nucleus, nucleolus.
Target Protein Families
TRAFAC class YlqF/YawG GTPase family
Target Research Area
Others
Target Synonyms
GNL3LGuanine nucleotide-binding protein-like 3-like protein
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