Rabbit anti-Human GUCY1A3 Polyclonal Antibody

The antibody against GUCY1A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GUCY1A3 (NP_000847.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-03199A

Number

Cat.No	ADA-03199A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	GUCY1A3
Target Synonyms	GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A3; GCS-alpha-3; GC-S-alpha-1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, 293T, A-549, Mouse brain, Rat kidney, Rat lung, Rat spleen, U-87MG	Application	ELISA, WB, IF/ICC

Cat.No

ADA-03199A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

GUCY1A3

Target Synonyms

GUCA3; MYMY6; GC-SA3; GUC1A3; GUCSA3; GUCY1A3; GCS-alpha-3; GC-S-alpha-1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, 293T, A-549, Mouse brain, Rat kidney, Rat lung, Rat spleen, U-87MG

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GUCY1A3 (NP_000847.2).	Target Species	Human
Immunogen Sequence	MFCTKLKDLKITGECPFSLLAPGQVPNESSEEAAGSSESCKATVPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAE	Uniprot ID	Q02108

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human GUCY1A3 (NP_000847.2).

Target Species

Human

Immunogen Sequence

MFCTKLKDLKITGECPFSLLAPGQVPNESSEEAAGSSESCKATVPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESICKLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTIAE

Uniprot ID

Q02108

Background Information

Uniprot Id

Q02108
Target Species

Human
Target Name

GUCY1A1
Target Full Name

Guanylate cyclase soluble subunit alpha-1
Target Involvement

Moyamoya disease 6 with achalasia (MYMY6)
Target Subcellular Location

Cytoplasm.
Target Protein Families

Adenylyl cyclase class-4/guanylyl cyclase family
Target Tissue Specificity

Detected in brain cortex and lung (at protein level).
Target Synonyms

GC S alpha 1; GC SA3; GCS alpha 1; GCS alpha 3; GCS-alpha-1; GCS-alpha-3; GCYA3_HUMAN; Guanylate cyclase 1 soluble alpha 3; Guanylate cyclase soluble subunit alpha 1; Guanylate cyclase soluble subunit alpha 3; Guanylate cyclase soluble subunit alpha-3; Guanylate cyclase; nitric oxide-sensitive; alpha-1 subunit; Guc1a1; GUC1A3; GUCA3; GUCSA3; Gucy1a1; Gucy1a3; MYMY6; nitric oxide-sensitive Guanylate cyclase; alpha-1 subunit; NOGC; alpha-1 subunit; Soluble guanylate cyclase large subunit
Target Background

Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3', 5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Rabbit anti-Human GUCY1A3 Polyclonal Antibody

Specifications

Immunogen Information

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