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Rabbit anti-Human HOXD12 Polyclonal Antibody

The antibody against HOXD12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HOXD12 (NP_067016.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03299A

The antibody against HOXD12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HOXD12 (NP_067016.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03299A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHOXD12
Target SynonymsHOX4H; HOXD12FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesNIH/3T3, A-549, Rat lungApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HOXD12 (NP_067016.3).Target SpeciesHuman
Immunogen SequenceMCERSLYRAGYVGSLLNLQSPDSFYFSNLRPNGGQLAALPPISYPRGALPWAATPASCAPAQPAGATAFGGFSQPYLAGSGPLGLQPPTAKDGPEEQAKFYAPEAAAGPEERGRTRPSFAPESSLAPAVAALKAAKYDYAGVGRATPGSTTLLQGAPCAPGFKDDTKGPLNLNMTVQAAGVASCLRPSLPUniprot IDP35452
Background Information
  • Uniprot Id

    P35452

  • Target Species

    Human

  • Target Name

    HOXD12

  • Target Full Name

    Homeobox protein Hox-D12

  • Target Function

    Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Abd-B homeobox family

  • Target Synonyms

    Homeobox protein Hox D12; Homeobox protein Hox-4H; Homeobox protein Hox-D12; Hox 4.7, mouse, homolog of; Hox 4H; HOX4H; HOXD12; HXD12_HUMAN

  • Target Background

    This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.

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