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The antibody against HPN was raised in rabbit using the Recombinant Human Serine protease hepsin protein (294-413AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HPN was raised in rabbit using the Recombinant Human Serine protease hepsin protein (294-413AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
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| Cat.No | ADC-06021A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HPN |
| Target Synonyms | HPN; TMPRSS1; Serine protease hepsin; Transmembrane protease serine 1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Serine protease hepsin protein (294-413AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P05981 |
Uniprot Id
P05981
Target Species
Human
Target Name
HPN
Target Full Name
Serine protease hepsin
Target Function
Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.
Target Subcellular Location
Cell membrane; Single-pass type II membrane protein. Apical cell membrane; Single-pass type II membrane protein.
Target Protein Families
Peptidase S1 family
Target Tissue Specificity
Detected in liver and kidney.
Target Synonyms
HPN; TMPRSS1; Serine protease hepsin; Transmembrane protease serine 1
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