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The antibody against HTATSF1 was raised in rabbit using the Human HTATSF1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against HTATSF1 was raised in rabbit using the Human HTATSF1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-53073A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HTATSF1 |
| Target Synonyms | HTATSF1HIV Tat-specific factor 1 antibody; Tat-SF1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human HTATSF1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43719 |
Uniprot Id
O43719
Target Species
Human
Target Name
HTATSF1
Target Full Name
17S U2 SnRNP complex component HTATSF1
Target Function
Functions as a general transcription factor playing a role in the process of transcriptional elongation. May mediate the reciprocal stimulatory effect of splicing on transcriptional elongation. In case of infection by HIV-1, it is up-regulated by the HIV-1 proteins NEF and gp120, acts as a cofactor required for the Tat-enhanced transcription of the virus.
Target Subcellular Location
Nucleus.
Target Protein Families
HTATSF1 family
Target Tissue Specificity
Widely expressed.
Target Synonyms
HTATSF1HIV Tat-specific factor 1; Tat-SF1
Target Background
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.
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