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The antibody against IAPP was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human Amylin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against IAPP was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human Amylin. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of HeLa cells using Amylin Polyclonal Antibody
| Cat.No | ADC-39337A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IAPP |
| Target Synonyms | amylin) antibody; Islet amyloid polypeptide antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human Amylin. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P10997 |
Uniprot Id
P10997
Target Species
Human
Target Name
IAPP
Target Full Name
Islet amyloid polypeptide
Target Function
Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
Target Subcellular Location
Secreted.
Target Protein Families
Calcitonin family
Target Research Area
Signal Transduction
Target Synonyms
Amylin; DAP; Diabetes associated peptide; Diabetes-associated peptide; IAP; IAPP; IAPP_HUMAN; Insulinoma amyloid peptide; Islet amyloid polypeptide (diabetes associated peptide, amylin); Islet amyloid polypeptide
Target Background
This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.
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