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The antibody against ICAM4 was raised in rabbit using the Recombinant Human Intercellular adhesion molecule 4 protein (20-140AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ICAM4 was raised in rabbit using the Recombinant Human Intercellular adhesion molecule 4 protein (20-140AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver cancer using ICAM4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using ICAM4 Antibody at dilution of 1:1002
| Cat.No | ADC-16965A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ICAM4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Intercellular adhesion molecule 4 protein (20-140AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14773 |
Uniprot Id
Q14773
Target Species
Human
Target Name
ICAM4
Target Full Name
Intercellular adhesion molecule 4
Target Function
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM4 is also a ligand for alpha-4/beta-1 and alpha-V integrins.
Target Subcellular Location
[Isoform Long]: Cell membrane; Single-pass type I membrane protein.; [Isoform Short]: Secreted.; Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, ICAM family
Target Tissue Specificity
Erythrocytes.
Target Synonyms
CD242; CD242 antigen ; ICAM-4; Icam4; ICAM4_HUMAN; Intercellular adhesion molecule 4; Landsteiner Wiener blood group glycoprotein; Landsteiner-Wiener blood group glycoprotein; LW; LW blood group protein
Target Background
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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