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The antibody against ICE1 was raised in rabbit using the Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ICE1 was raised in rabbit using the Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunofluorescence staining of Hela cell with ICE1 Antibody at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).2
| Cat.No | ADC-14878A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ICE1 |
| Target Synonyms | K0947_HUMAN antibody; KIAA0947 antibody; Uncharacterized protein KIAA0947 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Little elongation complex subunit 1 protein (1213-1505AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y2F5 |
Uniprot Id
Q9Y2F5
Target Species
Human
Target Name
ICE1
Target Full Name
Little elongation complex subunit 1
Target Function
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III. Specifically acts as a scaffold protein that promotes the LEC complex formation and recruitment and RNA polymerase II occupancy at snRNA genes in subnuclear bodies.
Target Subcellular Location
Nucleus. Nucleus, Cajal body.
Target Protein Families
ICE1 family
Target Synonyms
K0947_HUMAN; KIAA0947; Uncharacterized protein KIAA0947
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