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The antibody against IFFO1 was raised in rabbit using the Human IFFO1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against IFFO1 was raised in rabbit using the Human IFFO1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-53058A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IFFO1 |
| Target Synonyms | IFFO1 antibody; IFFOIntermediate filament family orphan 1 antibody; Tumor antigen HOM-TES-103 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human IFFO1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q0D2I5 |
Uniprot Id
Q0D2I5
Target Species
Human
Target Name
IFFO1
Target Full Name
Non-homologous end joining factor IFFO1
Target Function
Nuclear matrix protein involved in the immobilization of broken DNA ends and the suppression of chromosome translocation during DNA double-strand breaks (DSBs). Interacts with the nuclear lamina component LMNA, resulting in the formation of a nucleoskeleton that relocalizes to the DSB sites in a XRCC4-dependent manner and promotes the immobilization of the broken ends, thereby preventing chromosome translocation. Acts as a scaffold that allows the DNA repair protein XRCC4 and LMNA to assemble into a complex at the DSB sites.
Target Subcellular Location
Nucleus. Nucleus, nucleoplasm. Nucleus inner membrane. Nucleus matrix.
Target Protein Families
Intermediate filament family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
IFFO1; IFFOIntermediate filament family orphan 1; Tumor antigen HOM-TES-103
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