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Rabbit anti-Human IFT20 Polyclonal Antibody

The antibody against IFT20 was raised in rabbit using the Recombinant Human Intraflagellar transport protein 20 homolog protein (1-132AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-16710A

The antibody against IFT20 was raised in rabbit using the Recombinant Human Intraflagellar transport protein 20 homolog protein (1-132AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-16710A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIFT20
Target SynonymsIFT20Intraflagellar transport protein 20 homolog antibody; hIFT20 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Intraflagellar transport protein 20 homolog protein (1-132AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8IY31
Background Information
  • Uniprot Id

    Q8IY31

  • Target Species

    Human

  • Target Name

    IFT20

  • Target Full Name

    Intraflagellar transport protein 20 homolog

  • Target Function

    Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.

  • Target Subcellular Location

    Golgi apparatus, cis-Golgi network. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium. Cytoplasm, cytoskeleton. Golgi apparatus.

  • Target Tissue Specificity

    Expressed in almost all tissues.

  • Target Synonyms

    IFT20Intraflagellar transport protein 20 homolog; hIFT20

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