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The antibody against IFT27 was raised in rabbit using the Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against IFT27 was raised in rabbit using the Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human brain tissue using IFT27 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human testis tissue using IFT27 Antibody at dilution of 1:1002
| Cat.No | ADC-43907A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IFT27 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Intraflagellar transport protein 27 homolog protein (1-186AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BW83 |
Uniprot Id
Q9BW83
Target Species
Human
Target Name
IFT27
Target Full Name
Intraflagellar transport protein 27 homolog
Target Function
Small GTPase-like component of the intraflagellar transport (IFT) complex B that promotes the exit of the BBSome complex from cilia via its interaction with ARL6. Not involved in entry of the BBSome complex into cilium. Prevents aggregation of GTP-free ARL6. Required for hedgehog signaling. Forms a subcomplex within the IFT complex B with IFT25. Its role in intraflagellar transport is mainly seen in tissues rich in ciliated cells such as kidney and testis. Essential for male fertility, spermiogenesis and sperm flagella formation. Plays a role in the early development of the kidney. May be involved in the regulation of ureteric bud initiation.
Target Involvement
Bardet-Biedl syndrome 19 (BBS19)
Target Subcellular Location
Cell projection, cilium. Cytoplasm. Cell projection, cilium, flagellum.
Target Protein Families
Small GTPase superfamily, Rab family
Target Research Area
Signal Transduction
Target Synonyms
BBS19; Ift27; IFT27_HUMAN; Intraflagellar transport 27; Intraflagellar transport protein 27 homolog; Putative GTP binding protein RAY like; Putative GTP-binding protein RAY-like; Rab like protein 4 ; RAB member of RAS oncogene family like 4; Rab-like protein 4; RAYL
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