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The antibody against IK was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human IK. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against IK was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human IK. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of HeLa cells using IK Polyclonal Antibody
Western blot analysis of HELA KB SH-SY5Y 293T 3T3 lysis using IK antibody.2
| Cat.No | ADC-38427A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IK |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human IK. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13123 |
Uniprot Id
Q13123
Target Species
Human
Target Name
IK
Target Full Name
Protein Red
Target Function
Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1.; (Microbial infection) Required, together with SMU1, for normal splicing of influenza A virus NS1 pre-mRNA, which is required for the production of the exportin NS2 and for the production of influenza A virus particles. Not required for the production of VSV virus particles.
Target Subcellular Location
Nucleus. Nucleus, nucleoplasm. Chromosome. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
RED family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
chondrosarcoma associated protein 2 ; CSA2 ; Cytokine IK; IK; IK cytokine down regulator of HLA II ; IK factor; IK Gene; prer protein; Protein Red; Protein RER; RD element; RED protein; RED_HUMAN; RER
Target Background
The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2.
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