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Rabbit anti-Human IL25 Polyclonal Antibody

The antibody against IL25 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 33-177 of human IL25 (NP_073626.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-01569A

The antibody against IL25 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 33-177 of human IL25 (NP_073626.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-01569A ClonalityPolyclonal
Host SpeciesRabbitTarget NameIL25
Target SynonymsIL17E; IL25FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive Samples293T transfected with 17E/IL25ApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 33-177 of human IL25 (NP_073626.1).Target SpeciesHuman
Immunogen SequenceYSHWPSCCPSKGQDTSEELLRWSTVPVPPLEPARPNRHPESCRASEDGPLNSRAISPWRYELDRDLNRLPQDLYHARCLCPHCVSLQTGSHMDPRGNSELLYHNQTVFYRRPCHGEKGTHKGYCLERRLYRVSLACVCVRPRVMGUniprot IDQ9H293
Background Information
  • Uniprot Id

    Q9H293

  • Target Species

    Human

  • Target Name

    IL25

  • Target Full Name

    Interleukin-25

  • Target Function

    Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    IL-17 family

  • Target Tissue Specificity

    Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.

  • Target Synonyms

    IL 17E; IL 25; IL-17E; IL-25; IL17e; IL25; IL25_HUMAN; Interleukin 17E ; Interleukin 25 ; Interleukin-17E; Interleukin-25; Interleukin17E; Interleukin25; OTTHUMP00000027946; OTTHUMP00000246238; UNQ3120/PRO10272

  • Target Background

    The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants.

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