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Rabbit anti-Human Inhibin beta A Polyclonal Antibody

The antibody against Inhibin beta A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Inhibin beta A (NP_002183.1?) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08473A

The antibody against Inhibin beta A was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Inhibin beta A (NP_002183.1?) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08473A ClonalityPolyclonal
Host SpeciesRabbitTarget NameInhibin beta A
Target SynonymsEDF; FRP; Inhibin beta A (INHBA)FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liverApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human Inhibin beta A (NP_002183.1?).Target SpeciesHuman
Immunogen SequenceMPLLWLRGFLLASCWIIVRSSPTPGSEGHSAAPDCPSCALAALPKDVPNSQPEMVEAVKKHILNMLHLKKRPDVTQPVPKAALLNAIRKLHVGKVGENGYUniprot IDP08476
Background Information
  • Uniprot Id

    P08476

  • Target Species

    Human

  • Target Name

    INHBA

  • Target Full Name

    Inhibin beta A chain

  • Target Function

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    TGF-beta family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Activin beta-A chain; EDF; Erythroid differentiation factor; Erythroid differentiation protein; Follicle stimulating hormone releasing protein; FRP; FSH releasing protein; INHBA; INHBA_HUMAN; Inhibin beta A chain; Inhibin beta A subunit; Inhibin, beta 1; Inhibin, beta A (activin A, activin AB alpha polypeptide)

  • Target Background

    This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. The encoded protein also plays a role in eye, tooth and testis development. Elevated expression of this gene may be associated with cancer cachexia in human patients.

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