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The antibody against IRAK2 was raised in rabbit using the Recombinant Human Interleukin-1 receptor-associated kinase-like 2 protein (1-270AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against IRAK2 was raised in rabbit using the Recombinant Human Interleukin-1 receptor-associated kinase-like 2 protein (1-270AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human colon cancer using IRAK2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human liver cancer using IRAK2 Antibody at dilution of 1:1002
| Cat.No | ADC-45297A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | IRAK2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Interleukin-1 receptor-associated kinase-like 2 protein (1-270AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43187 |
Uniprot Id
O43187
Target Species
Human
Target Name
IRAK2
Target Full Name
Interleukin-1 receptor-associated kinase-like 2
Target Function
Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Target Protein Families
Protein kinase superfamily, TKL Ser/Thr protein kinase family, Pelle subfamily
Target Tissue Specificity
Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Target Research Area
Immunology
Target Synonyms
il1rak2; Interleukin 1 receptor associated kinase 2; Interleukin 1 receptor associated kinase like 2; Interleukin-1 receptor-associated kinase-like 2; IRAK 2; IRAK-2; Irak2; IRAK2_HUMAN; MGC150550
Target Background
IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
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