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Rabbit anti-Human ITGA1 Polyclonal Antibody

The antibody against ITGA1 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 920-980 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.

ADC-13023A

The antibody against ITGA1 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 920-980 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-13023A ClonalityPolyclonal
Host SpeciesRabbitTarget NameITGA1
FormLiquidSpecies ReactivityHuman
Storage BufferPH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBSPurification MethodThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide from Human protein at AA range: 920-980Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP56199
Background Information
  • Uniprot Id

    P56199

  • Target Species

    Human

  • Target Name

    ITGA1

  • Target Full Name

    Integrin alpha-1

  • Target Function

    Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

  • Target Subcellular Location

    Membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Integrin alpha chain family

  • Target Synonyms

    CD 49a; CD49 antigen-like family member A; CD49a; CD49a antigen; Integrin alpha-1; ITA1_HUMAN; Itga 1; ITGA1; Laminin and collagen receptor; Very late activation protein 1; VLA 1; VLA-1; VLA1

  • Target Background

    This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.

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