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The antibody against JAGN1 was raised in rabbit using the Recombinant Human Protein jagunal homolog 1 protein (1-39AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against JAGN1 was raised in rabbit using the Recombinant Human Protein jagunal homolog 1 protein (1-39AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
$299.00
| Cat.No | ADC-19215A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | JAGN1 |
| Target Synonyms | JAGN1; Protein jagunal homolog 1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein jagunal homolog 1 protein (1-39AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N5M9 |
Uniprot Id
Q8N5M9
Target Species
Human
Target Name
JAGN1
Target Full Name
Protein jagunal homolog 1
Target Function
Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.
Target Involvement
Neutropenia, severe congenital 6, autosomal recessive (SCN6)
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Jagunal family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
JAGN1; Protein jagunal homolog 1
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