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Rabbit anti-Human KDM3B Polyclonal Antibody

The antibody against KDM3B was raised in rabbit using the Fusion protein of Human KDM3B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-29812A

The antibody against KDM3B was raised in rabbit using the Fusion protein of Human KDM3B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-29812A ClonalityPolyclonal
Host SpeciesRabbitTarget NameKDM3B
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human KDM3BTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ7LBC6
Background Information
  • Uniprot Id

    Q7LBC6

  • Target Species

    Human

  • Target Name

    KDM3B

  • Target Full Name

    Lysine-specific demethylase 3B

  • Target Function

    Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    JHDM2 histone demethylase family

  • Target Tissue Specificity

    Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    5qNCA; C5orf7; JHDM2B; JmjC domain containing histone demethylation protein 2B; JmjC domain-containing histone demethylation protein 2B; jmjd1b; Jumonji domain containing 1B; Jumonji domain containing protein 1B; Jumonji domain-containing protein 1B; KDM3B; KDM3B_HUMAN; KIAA1082; Lysine (K) specific demethylase 3B ; Lysine-specific demethylase 3B; NET22; Nuclear protein 5qNCA

  • Target Background

    Predicted to enable chromatin DNA binding activity; histone H3-methyl-lysine-9 demethylase activity; and transcription coregulator activity. Predicted to be involved in histone H3-K9 demethylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma.

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