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The antibody against KRT80 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 242-452 of human KRT80 (NP_872313.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
The antibody against KRT80 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 242-452 of human KRT80 (NP_872313.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on IF/ICC, ELISA.
| Cat.No | ADA-00437A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | KRT80 |
| Target Synonyms | KB20; KRT80 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 242-452 of human KRT80 (NP_872313.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6KB66 | Immunogen Sequence |
Uniprot Id
Q6KB66
Target Species
Human
Target Name
KRT80
Target Full Name
Keratin, type II cytoskeletal 80
Target Synonyms
CK 80; CK-80; CK80; Cytokeratin 80; Cytokeratin-80; K 80; K2C80_HUMAN; K80; KB20; Keratin 80; Keratin; Keratin-80; KRT 80; Krt80; type II cytoskeletal 80; Type II keratin; Type-II keratin Kb20
Target Background
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
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