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The antibody against LMBR1L was raised in rabbit using the Human LMBR1L as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against LMBR1L was raised in rabbit using the Human LMBR1L as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
$600.00
| Cat.No | ADC-52859A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | LMBR1L |
| Target Synonyms | LMBR1L antibody; KIAA1174 antibody; LIMR antibody; UNQ458/PRO783Protein LMBR1L antibody; Limb region 1 protein homolog-like antibody; Lipocalin-1-interacting membrane receptor antibody; LIMR antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Human LMBR1L | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UX01 |
Uniprot Id
Q6UX01
Target Species
Human
Target Name
LMBR1L
Target Full Name
Protein LMBR1L
Target Function
Plays an essential role in lymphocyte development by negatively regulating the canonical Wnt signaling pathway. In association with UBAC2 and E3 ubiquitin-protein ligase AMFR, promotes the ubiquitin-mediated degradation of CTNNB1 and Wnt receptors FZD6 and LRP6. LMBR1L stabilizes the beta-catenin destruction complex that is required for regulating CTNNB1 levels. Acts as a LCN1 receptor and can mediate its endocytosis.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
LIMR family
Target Tissue Specificity
Expressed in testis, pituitary gland, adrenal gland, trachea, placenta, thymus, cerebellum, stomach, mammary gland, spinal cord. A weaker expression is detected in colon, pancreas, and prostate.
Target Synonyms
LMBR1L; KIAA1174; LIMR; UNQ458/PRO783Protein LMBR1L; Limb region 1 protein homolog-like; Lipocalin-1-interacting membrane receptor; LIMR
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